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High-Performance Liquid Chromatograph SY-9250 for Organic Compounds - Trusted China Suppliers & Factory
🎯 Main Use: Separation, Analysis, and Purification of Organic Compounds
⚙️ Working Conditions
| Power Supply | Single phase 220V ±10%, 50/60Hz |
| Environmental Temperature | 15–35℃ |
| Environmental Humidity | <85% |
💧 Four Element Infusion Pump
Series-connected double plunger reciprocating pump, double ball one-way valve, dual efficiency ensures high-pressure sealing.
- ★ Independent four-channel design, any 2/3/4 channel online mixing — capable of achieving ≥ 4 types of solvent mixing.
- ★ Standard 4-channel online degassing machine; upgradeable to 1-channel online degassing for needle washing solution — reduces bubbles and increases injection accuracy.
🔬 Variable Wavelength UV Visible Detector
Advanced optical path design with powerful DSP drive. Dual lights can be automatically controlled and switched, avoiding manual switching delays and errors. The insulation device ensures sufficient and stable energy throughout the entire wavelength range, achieving lower detection limits and wider detection ranges. The side deuterium lamp positioning system enables fast and easy lamp replacement.
| Light Source | Deuterium Lamp & Tungsten Lamp (light source number ≥ 2) |
| Wavelength Range | 190–900 nm |
| Wavelength Calibration | Automatic correction via deuterium lamp and built-in holmium oxide filter |
✨ Fluorescence Detector
Adopting a newly designed optical system with ultra-high sensitivity and ultra-fast analysis capability. The position of the fluorescent detector's lamp and detection pool does not need to be adjusted, making maintenance simple.
💡 Evaporative Luminescence Detector (ELSD)
A brand new optical path design with excellent detection performance — real-time monitoring of temperature, pressure, and flow, with sound and light alarms for abnormal situations.
🌐 High Universality
📈 Gradient Compatible
🔗 Compatible with Any HPLC
📦 Compact Size
Detects any compound with volatility lower than the mobile phase. Gradient compatibility improves separation and shortens analysis time. Easy to use and small in size.
🔭 Refractive Index Detector (RID)
| Measurement Method | Refractive Method |
| Refractive Index Range | 1.00 – 1.75 |
🌡️ Column Oven
Large capacity space design accommodating at least four 300mm long chromatography columns.
Intelligent temperature control design with forced air circulation system ensures rapid temperature attainment and stability. Standard temperature and time programming supports stage constant temperature and interval heating and cooling.
💉 Injection System
| Injection Mode | Full loop injection, partial loop fill injection, μL pickup injection |
| Injection Volume | ≥108 positions (1.5mL); 2×96 positions plate injection optional |
🖥️ Workstation
- ✔ Regulatory Compliance: Complies with FDA 21 CFR Part 11 / GMP / GLP specifications. Database version ensures data security, automatic backup, electronic signature, audit tracking, and multi-level user permission management.
- ✔ Advanced Data Processing: Instrument control parameters, data acquisition, automatic peak width, automatic threshold algorithm, adaptive data acquisition, and automatic adjustment algorithm ensure optimal integration results.
- ✔ Diagnosis & Maintenance: Automatically diagnoses the performance of all instrument components, with built-in analysis of common faults.
- ✔ Early Maintenance Warning: Records cumulative usage time and replacement frequency of major consumables, and actively reminds users to maintain and replace them on schedule.
- ✔ Built-in IQ Verification: Automatic Installation Verification (IQ) for convenient certification of instrument software and hardware.
❓ Frequently Asked Questions (FAQ)
Q1
What types of compounds can the SY-9250 HPLC system separate and analyze?
The SY-9250 is designed for the separation, analysis, and purification of a wide range of organic compounds. With its multiple detector options — including UV-Vis, Fluorescence, ELSD, and RID — it can handle both volatile and non-volatile compounds across diverse application fields such as pharmaceuticals, food safety, environmental testing, and chemical research.
Q2
How many solvents can the four-element infusion pump mix simultaneously?
The four-element infusion pump features an independent four-channel design that supports any combination of 2, 3, or 4 channels for online mixing. This allows the system to achieve ≥ 4 types of solvent mixing simultaneously, providing exceptional flexibility for complex gradient elution methods.
Q3
What is the wavelength range of the UV Visible detector, and how is calibration performed?
The variable wavelength UV-Vis detector covers a broad range of 190–900 nm, enabling detection from the UV to the near-infrared spectrum. Wavelength calibration is performed automatically using a built-in deuterium lamp correction system combined with a holmium oxide filter, ensuring measurement accuracy without manual intervention.
Q4
Is the SY-9250 HPLC system compliant with GMP and FDA 21 CFR Part 11 regulations?
Yes. The integrated workstation software fully complies with FDA 21 CFR Part 11, GMP, and GLP specifications. It provides comprehensive data security features including automatic backup, electronic signature support, full audit tracking, and multi-level user permission management — making it suitable for regulated laboratory environments.
Q5
Can the ELSD detector be used with any HPLC system?
Yes. The Evaporative Luminescence Detector (ELSD) is designed with broad compatibility and can be connected and used with any standard HPLC system. It can detect any compound whose volatility is lower than the mobile phase, making it highly versatile for universal compound detection, especially for compounds that lack UV absorption.
Q6
What injection modes are supported by the SY-9250 autosampler?
The SY-9250 injection system supports three flexible injection modes: full loop injection, partial loop fill injection, and μL pickup injection. The system accommodates ≥ 108 sample positions (1.5mL vials), with an optional 2×96-position microplate injection configuration for high-throughput analytical workflows.